FANCD2 - significado y definición. Qué es FANCD2
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Qué (quién) es FANCD2 - definición


FANCD2         
  •  doi = 10.1128/MCB.00465-12 }}</ref> [[RAD51]] plays a major role in [[homologous recombination]]al repair of DNA during double strand break repair. In this process, an ATP dependent DNA strand exchange takes place in which a single strand invades base-paired strands of homologous DNA molecules.  RAD51 is involved in the search for homology and strand pairing stages of the process.
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
FANCD2 (gene)
Fanconi anemia group D2 protein is a protein that in humans is encoded by the FANCD2 gene. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2 (this gene), FANCE, FANCF, FANCG, FANCI , FANCJ, FANCL, FANCM, FANCN and FANCO.
FANCD2OS         
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
Fanconi Anemia Opposite Strand Transcript protein is a predicted protein that in humans is encoded by the FANCD2OS gene. The name is derived from mRNA transcribed from the strand complementary to the FANCD2 gene.
FAN1         
  • Figure 1. Color coded structure of FAN1 monomer with the SAP shown in blue and purple, TPR in orange, and VRR_Nuc in green. The secondary features of the SAP domain are labeled. Created in PyMOL from PDB structure 4RID.<ref name="Zhao_2014" />
  •  doi = 10.1126/science.1258973 }}</ref>
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
FAN1 (gene)
FANCD2/FANCI-associated nuclease 1 (KIAA1018) is an enzyme that in humans is encoded by the FAN1 gene. It is a structure dependent endonuclease and a member of the myotubularin-related class 1 cysteine-based protein tyrosine phosphatases.